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KMID : 1103720120670010017
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Journal of the Korean Society of Radiology
2012 Volume.67 No. 1 p.17 ~ p.23
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Percutaneous Transluminal Biopsy Using 7-F Forceps for Diagnosing Malignant Biliary Obstruction
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Bahn Young-Eun
Kim Young-Hwan
Ahn Eun-Jung
Kim Si-Hyung
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Abstract
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Purpose: To evaluate the usefulness of the percutaneous transluminal biopsy using 7-F forceps for diagnosing malignant biliary obstruction.
Materials and Methods: One hundred and seven consecutive patients with obstructive jaundice underwent transluminal forceps biopsy. The lesions involved the common bile duct (n = 33), common hepatic duct (n = 13), hilum (n = 17), right or left intrahepatic bile duct (n = 32), multiple sites (extra- and intrahepatic ducts, n = 7), or anastomotic sites (n = 5). In each patient, an average of three specimens was taken with 7-F biopsy forceps through a transhepatic biliary drainage tract. The final diagnosis was confirmed with pathologic findings, or a clinical and radiologic follow-up.
Results: The final diagnoses showed malignancies in 75 patients and benign biliary obstructions in 32 patients. Pathologic classifications of malignancies established by forceps biopsy included 67 adenocarcinomas, 1 adenosquamous cell carcinoma, and 1 hepatocelluar carcinoma. There were 6 false-negative diagnoses. The diagnostic performance of transluminal forceps biopsy in malignant biliary obstruction had a sensitivity of 92%, specificity of 100%, positive predictive value of 100%, a negative predictive value of 84.2%, and an accuracy of 94.2%.
Conclusion: Percutaneous transluminal forceps biopsy is a safe procedure that is easy to perform through a transhepatic biliary drainage tract. It is a highly accurate technique for diagnosing malignant biliary obstructions.
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KEYWORD
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Bile Ducts, Biopsy , Bile Ducts, Percutaneous Drainage
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